Do the data support Haldanes prediction that individuals with the S allele have greater resistance to malaria than AA individuals?
It wasn’t until the 1960’s that data that could address this prediction became available. Below you will find the original data7 that were used to test Haldane’s hypothesis. They are a compilation of 10 independent studies on the incidence of severe plasmodium infection among children with or without the sickle-cell allele. Exercise: Examine the data, and show whether the evidence supports or rejects the hypothesis that the S allele confers resistance to infection by the plasmodium that causes malaria. (Most of the individuals in the category ‘with S allele’ were heterozygotes, but a few were SS homozygotes.) Method for Analysis: For each of the ten populations, calculate the frequency of infection among people with the S allele, and among people without. If Haldane’s hypothesis is correct, then there should be higher rates of infection among AA individuals than among AS or SS individuals. Does this appear to be true? Could we have gotten this result by chance, even if the S allele has
Related Questions
- Only individuals with a user ID on the Access Data Backup Client software will be able to administer its functions. Can users administer backups for their own machines?
- Explain how data is physically secured. Is the data center locked-down to authorized individuals?
- Does Total Access Analyzer support Access Data Projects (ADPs)?
