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Do the complement component products (C1q, C4, C5, factor D) cross react with rat?

April 26, 2017C4 C5 complement component cross Factor products react

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Do the complement component products (C1q, C4, C5, factor D) cross react with rat?

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The anti-C3, anti-C4 and anti-C5 antibodies cross react with mouse and rat complement components. You should be able to use them in ELISA, histochemistry, Western blotting and immunodiffusion. The complexes formed are smaller than for human so they are less well suited for nephelometric analysis. Unfortunately we do not have any data on cross reactivity with factor D.