Do the 3DNA reagents experience photobleaching?
Many fluorescent dyes experience photobleaching, or fading, of the signal after repeated excitation-emission cycles. The fluorescent dye molecules attached to 3DNA reagents are chemically similar to their dNTP counterparts, and will fade over time. Ways to avoid photobleaching include protecting the dyes from light and avoiding excessive laser power settings on some scanners. For a further explanation please contact Technical Support.
