Do symptoms develop if gabapentin is suddenly discontinued?
Like other psychopharmacologic agents, gabapentin should be discontinued gradually. Withdrawal reactions have been occasionally treported, mostly in people who have abruptly stopped taking large doses of gabapentin. Only when necessary because of a serious side effect, should gabapentin be suddenly discontinued.
There are no specific symptoms that have been described following the abrupt discontinuation of gabapentin, other than the seizures that sometimes follow the rapid discontinuation of any anticonvulsant. Only when necessary because of a serious side effect, should gabapentin be suddenly discontinued.