Do skin tags need to be sent for biopsy?
Most typical small skin tags may be removed without sending tissue for microscopic examination or biopsy. However, there are some larger or atypical growths that may be removed and sent to a pathologist for examination under a microscope to make sure that the tissue is really a skin tag and nothing more. Additionally, skin bumps that have bled or rapidly changed may also need pathologic examination. Some common skin tag look-alikes include friendly barnacles called seborrheic keratosis, common moles, warts, neurofibroma, and a fatty mole called nevus lipomatosus. While extremely rare, there are a few reports of skin cancers found in skin tags. Skin cancers like basal cell carcinoma, squamous cell carcinoma, and malignant melanoma may rarely mimic skin tags, as described above.