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Do polycystic-appearing ovaries affect the risk of cardiovascular disease among women with polycystic ovary syndrome?

April 26, 2017affect cardiovascular disease ovaries ovary polycystic risk SYNDROME women

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Do polycystic-appearing ovaries affect the risk of cardiovascular disease among women with polycystic ovary syndrome?

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Loucks TL; Talbott EO; McHugh KP; Keelan M; Berga SL; Guzick DS Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania 15213, USA. OBJECTIVE: To determine if polycystic-appearing ovaries (PAO) are associated with differences in risk factors for cardiovascular disease among women with polycystic ovary syndrome (PCOS). DESIGN: Case-control sub-study. SETTING: Division of Reproductive Endocrinology, Magee-Womens Hospital. PATIENT(S): Women with PCOS (n = 63) and non-PCOS controls (n = 56). INTERVENTION: Transvaginal ultrasonography and single sample venipuncture. MAIN OUTCOME MEASURE(S): Ultrasound ovarian appearance, fasting insulin, lipoproteins, androgens, LH/FSH ratio, anthropomorphic measurements, and blood pressure. RESULT(S): Women with PCOS had higher androgen and fasting insulin levels, a more adverse lipid profile, greater waist-hip and LH/FSH ratios, and a larger ovarian volume than controls.