Do patients with the MMF lesion have any specific clinical symptoms?
A. It has been suggested that vaccination and localized MMF lesions might be associated with a multi-system disorder. However, the linkage of MMF with a multi-system disorder has been suggested by comparing an unmatched population of similar patients who underwent biopsies of the deltoid muscle and patients with the MMF lesion suffering from diffuse muscle pain. However, the prevalence of MMF in the general population is not known, and the patients studied were not matched with a control group – a necessary step to rule out confounding factors and other possible explanations. It is also unclear whether patients without biopsy evidence of MMF, who had previously received an aluminium-containing vaccine, might have the typical lesion of MMF elsewhere in the muscle, with it being missed on biopsy.
