Do older adults need higher repletion doses of vitamin D3 than younger adults?
Susan J. Whiting 1 *, Mona S. Calvo 2 Molecular Nutrition & Food Research 3 May 2010 1College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Saskatchewan, Canada 2Office of Applied Research and Safety Assessment Center for Food Safety and Applied Nutrition, US Food and Drug Administration Laurel, MD, USA email: Susan J. Whiting (susan.whiting@usask.ca Correspondence to Susan J. Whiting, College of Pharmacy and Nutrition, University of Saskatchewan, 110 Science Place, Saskatoon, Saskatchewan, S7N 5C9 Canada Fax:+1-306-966-6377 We conducted an examination of recent studies to determine whether older adults (65 years) need higher levels of supplementary vitamin D than young adults when attempting to replete vitamin D status in deficient subjects, i.e. those with levels of 25-hydroxyvitamin D less than 75 nmol/L. As data on repletion with vitamin D2 have recently been published, we restricted our discussion to the use of vitamin D3 from dietary supplements, prescriptions