Do mushrooms or LSD cause brain damage? Are mushrooms safer than LSD?
Neither mushrooms or LSD are known to cause brain damage. The active ingredient in mushrooms (psilocybin) is an extremely close chemical relative to the brain’s own neurotransmitter, serotonin. Both drugs are remarkably non-toxic, with no known human death from overdose, even at ridiculously high dosage levels. All psychedelics carry a certain slight risk of long-term adverse effects, but these effects are psychological in nature (flashbacks, PHPD, etc.