DO LAB RESULTS VARY DEPENDING ON HOW VENOUS SAMPLES ARE OBTAINED?
Although venipuncture and aspiration from a peripheral venous catheter generally produce blood samples of similar quality from patients who appear healthy, venipuncture may be a more reliable means of obtaining samples when glucose, potassium, or bicarbonate measurements are needed. Zlotowski et al evaluated 32 volunteers from the emergency department staff of a tertiary care teaching hospital. Subjects served as their own controls; venipuncture and withdrawal of a blood sample were performed on one upper extremity while a peripheral catheter was concurrently placed in the other. Through the peripheral catheter, subjects received a 200-mL bolus of normal saline solution during a 10-minute period. Following a two-minute waiting period, a 12-mL aspirate was taken through the saline solution lock. A second withdrawal of 12 mL through the lock followed. These three samples were evaluated for 19 laboratory values, including complete blood count; electrolyte, blood urea nitrogen, creatinine,
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