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Do I need to use a solvent when compounding medications into DiffusiMAX?

April 26, 2017compounding DiffusiMAX medications solvent

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Do I need to use a solvent when compounding medications into DiffusiMAX?

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Medications can be mixed with solvents prior to incorporating into DiffusiMAX. The solvent may enhance drug release of the medication presumably by reducing the viscosity of the PLO gel. Use of the solvent may also allow for easier incorporation of the medication into DiffusiMAX. It is important when mixing a PLO gel- based prescription that the recommended amount of solvent is not exceeded. Doing so will result in a diluted final product that will be unattractive in appearance. In general, use enough solvent to make the medication into a paste. It is not necessary to dissolve the drug completely with the solvent. Final dissolving will take place in the gel over a short period of time. For tables showing the proper solvent to use with a given medication please see COMPOUNDING MANUAL on this Website.