Do Hematology instruments need to be tested for HBOC interferences?
Most hematology parameters e.g., WBC, RBC, and platelet counts and WBC differentials are not affected by the presence of either HBOC. However, techniques which rely on the direct measurement of hemoglobin may be affected since the measurement of hemoglobin (Hb) would be the combination of RBC Hb plus the HBOC.