Do gender and race influence survival in patients with non-small cell lung cancer brain metastases?
G. M. Videtic, C. A. Reddy, S. T. Chao, T. W. Rice, D. J. Adelstein, G. H. Barnett, T. M. Mekhail, M. A. Vogelbaum and J. H. Suh Cleveland Clinic Foundation, Cleveland, OH 7153 Background: To explore gender, race and their interactions in the setting of NSCLC brain metastases only, a single-institution brain database was analyzed, using the RTOG recursive partitioning analysis (RPA) brain metastases classification. Methods: From 1/82 to 9/04, 831 NSCLC pts with brain metastases were registered. RPA criteria for analysis were: class I- Karnofsky performance status (KPS) 70, age<65 years, primary tumor controlled, no extracranial metastases; class III- KPS<70; class II- all others. Results: Median follow-up was 5.4 months (m) (range 0–122.9). Median age was 62.4 (range 25–90). Median KPS was 80 (range 20–100). There were 485 males [M] (58.4%) and 346 females [F] (41.6%). 824 pts (99%) were either African-American (AA; n = 142[17%]) or White (W; n = 682[83%]). Pts characteristics were bal
