Do food antigens play a role in the pathogenesis of some cases of human glomerulonephritis?
Author van der Woude FJ; Hoedemaeker PJ; van der Giessen M; de Graeff PA; de Monchy J; The TH; van der Hem GK Source Clin Exp Immunol, 1983 Mar, 51:3, 587-94 Abstract Circulating immune complexes after a test meal were measured with three methods (PEG precipitation, Clq-ELISA and the indirect granulocyte phagocytosis test) in 10 controls, two symptomless persons with selective IgA deficiency and 14 patients with various types of glomerulonephritis, of which two patients (with idiopathic membranous glomerulopathy and local focal glomerulonephritis) also had selective IgA deficiency. The PEG and Clq-ELISA test did not show significant differences between the groups. In the two symptomless persons with selective IgA deficiency and in the patient with local focal glomerulonephritis and selective IgA deficiency the indirect granulocyte phagocytosis test (IGFT) showed a reproducible increase in IgG, IgM and complement containing immune complexes. In the last patient multiple food antigens we
