Do environmental allergies play a bigger role in EGID than originally thought?
They might, in some cases, it depends on the specific patient and the type of allergies. Most likely, yes, environmental factors can play a role in eosinophilic disorders. Allergic reactions do not occur exclusively in the GI tract; various systems are processes are linked. What you breathe in might make you more prone to react. Dr Marc Rothenberg of Cincinnati Childrens has shown in his research that mice develop EE after mold has been introduced to their lungs. This process is not proven in humans, but we think that people develop EE as a combination of genetic and environmental factors; someone might be more prone to develop EE genetically, but the disorder only develops when a specific set of conditions in their outside environment trigger the response. Limiting exposure to known environmental allergens is recommended to help reduce reactions.
