Do doctors use genetics or family history when assessing a persons risk of developing venous thromboembolism?
Dr. Shuman: Yes, physicians do use family history when evaluating a person’s risk of developing venous thromboembolism. It is standard practice to take a detailed family history of phlebitis, or “blood clots to the lung” (pulmonary embolism) from any patient who develops thromboembolic disease. Genetic disorders that predispose an individual to thrombosis are inherited in an autosomal dominant pattern with variable penetrance. Similarly, physicians usually take a detailed family history from patients being evaluated for major surgery. 23andMe: Are there any precautions that a person can take to reduce his/her risk of venous thromboembolism? Dr. Shuman: Most thromboembolic events are triggered by specific situations. Major surgery by itself is one of these, particularly knee and hip replacement, spine, and brain surgery. Individuals should discuss their risk of post-operative thrombosis with their physician and surgeon before the operation. Depending on the type and duration of surgery,
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