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Do DGGE and LightScanner have the same sensitivity as sequencing for detecting mutations?

April 26, 2017detecting mutations sequencing

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Do DGGE and LightScanner have the same sensitivity as sequencing for detecting mutations?

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For the PTEN coding region, our lab found that both DGGE and LightScanner picked up all the mutations detected by sequencing. Whenever an abnormality is noted, we do confirmation by sequencing.