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Do CD8 antibodies affect the binding of Tetramer to specific CD8 T cells?

April 26, 2017affect antibodies Binding cells t tetramer

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Do CD8 antibodies affect the binding of Tetramer to specific CD8 T cells?

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The mutation that greatly reduces the binding of iTAg Tetramer to human and rhesus macaque CD8 also minimizes the aberrant effect that some CD8 antibodies have on the specific binding of MHC Class I Tetramer.