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Do asparagine-linked carbohydrate chains in glycoproteins have a preference for beta-bends?

April 26, 2017carbohydrate Chains glycoproteins

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Do asparagine-linked carbohydrate chains in glycoproteins have a preference for beta-bends?

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X-ray structures of the conformation of carbohydrate moieties and connected regions of glycoproteins are summarized. Evidence is presented that there is some preference for carbohydrate attachment at beta-bends. Evolution may have favored glycosylation to occur at bends to ensure free mobility of the carbohydrate moieties.