Do any over-the-counter medications conflict with Adderall?
1. Advil (ibuprofen) temporarily increases Adderall tolerance. If your morning dose isn’t kicking in like normal, and you’ve taken Advil recently, do not start popping more pills. That will end badly for you. Somehow (and I don’t know the science behind this) ibuprofen seems to block the Adderall effect. Just ride it out and chalk this day up as a loss. 2. Mucinex (expectorant) drastically accelerates and corrupts the Adderall high. I do not recommend taking a mucus expectorant like Mucinex with your Adderall dose. It’s too much. It is not a pleasant feeling. Same goes for cough syrup (e.g., Robatussin). If you’re sick and thus need to take an expectorant, cut your Adderall dose for that day in half, or better yet don’t take it at all.