Do anticholinergic agents suppress uterine peristalsis and sporadic myometrial contractions at cine MR imaging?
PURPOSE: To prospectively evaluate anticholinergic drug effects on uterine peristalsis and sporadic myometrial contractions, as well as on intestinal motion, with cine magnetic resonance (MR) imaging. MATERIALS AND METHODS: This prospective study was approved by the institutional review board; informed consent was obtained from all participants. Twenty-one women (mean age, 29.3 years +/- 4.0 [standard deviation]) underwent MR imaging during the follicular through periovulatory phases (cycle days 5-26). Before and after injection of an anticholinergic agent, 60 serial half-Fourier rapid acquisition with relaxation enhancement MR images were obtained within 2 minutes in the midsagittal uterine plane. Evaluations were performed independently and separately in random order by two radiologists who were blinded to whether an anticholingeric agent had been administered. Uterine peristalsis was evaluated for frequency (paired t test), predominant direction (McNemar test), degree of endometrial
