Do antibiotics administered at the time of central venous catheter removal interfere with the evaluation of colonization?
OBJECTIVE: Catheter colonization is commonly used as an end point in studies on central venous catheter (CVC) infections. This study aimed at comparing the rates of catheter colonization in patients according to the administration of antibiotics at removal. DESIGN: Prospective study over a 5-year period. All patients with a CVC removed without suspicion of CVC infection were included. SETTING: An adult medical/surgical intensive care unit at a university teaching hospital. PATIENTS: A total of 472 patients with CVC inserted for a mean CVC duration of 6.0 +/- 3.7 days were included. METHODS: Antibiotics at removal was defined as antibiotics administered within 48[Symbol: see text]h before CVC removal, and CVC colonization as catheter tip culture yielding > or = 10(3) colony-forming units per milliliter. INTERVENTIONS: None. MEASUREMENTS AND RESULTS: Of 472 patients, 302 (64%) were receiving antibiotics at removal. The number of CVC colonizations per number of CVCs inserted was 4.7% (22
Related Questions
- What if an emergency exists and a child needs to be removed from the residence immediately, does the CAFAS have to be administered before the emergency removal can take place?
- Do antibiotics administered at the time of central venous catheter removal interfere with the evaluation of colonization?
- Can antibiotics be administered at the same time as Flaminal® Hydro/Forte?
