Difference Between CopyDxSM and GenomeDx Q: CopyDxSM and GenomeDx sound very similar. What are the similarities and differences between these two tests?
• Both tests, CopyDxTM and GenomeDx, allow to determine how many copies a person carries for a certain gene. • CopyDxTM is based on the use of quantitative PCR (qPCR) technology. This targeted assay can be used to identify a deletion or duplication of a single gene or a known partial gene deletion or duplication in a known gene of interest. It is possible to differentiate between a whole or partial gene deletion/duplication although the exact size/boundaries of the abnormality cannot be determined. • GenomeDx is a specially designed, oligonucleotide microarray used for Comparative Genomic Hybridization (oligo aCGH). In one single assay, the entire genome is evaluated for chromosomal aneuploidy as well as regions of gains and losses. This test may establish the size and position of breakpoints of deletions or duplications in reference to individual genes, BAC or FISH clones, or microsatellite markers in the region. Technical limits apply and depend predominantly on the number and densit
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- Difference Between CopyDxSM and GenomeDx Q: CopyDxSM and GenomeDx sound very similar. What are the similarities and differences between these two tests?
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