Did the study authors in the 2008 Neurology article reach incorrect conclusions?
The study authors themselves highlighted the speculative nature of their conclusions. Their article was based on non-controlled case reports from four consumers. In each of the cases, an extreme amount of denture adhesive was used for years, two or more tubes of product per week, compared with the one tube of product every three to 10 weeks considered typical. What is not in doubt is the strong safety record of zinc-containing denture adhesives. First cleared for marketing in the United States by FDA roughly 15 years ago, these products are very safe when used as directed and adverse events are extremely rare.