Important Notice: Our web hosting provider recently started charging us for additional visits, which was unexpected. In response, we're seeking donations. Depending on the situation, we may explore different monetization options for our Community and Expert Contributors. It's crucial to provide more returns for their expertise and offer more Expert Validated Answers or AI Validated Answers. Learn more about our hosting issue here.

Could the use of a non-FDA approved regimen (vaginal misoprostol) explain the risk of C. sordellii infection?

April 26, 2017Approved explain infection misoprostol Regimen risk sordellii vaginal

0

Posted

Could the use of a non-FDA approved regimen (vaginal misoprostol) explain the risk of C. sordellii infection?

1 Answer

0

Posted

Although oral use of misoprostol is specified in the FDA-approved regimen, in the U.S., vaginal use of misoprostol in association with mifepristone is the norm. It is therefore expected that most deaths would be recorded among users of vaginal misoprostol, since there is almost no oral use. Consequently, it is almost impossible to draw conclusions about oral versus vaginal use. Indeed, hundreds of thousands of women in Europe and other places have used misoprostol vaginally, and no similar infections have been recorded in those women.