could pose a problem in individuals that already have impaired kidney function. 3.6: Is creatinine toxic to the kidneys?
creatine. It is not toxic to the kidneys at all. Creatinine levels are commonly used as a tool to determine kidney function, as high creatinine levels are commonly a symptom (not a cause) of impaired kidney function. 3.7: Can creatine harm the liver? In one animal model, high doses of creatine can lead to inflammation of the liver. It is important to note that rodent models are particularly misleading with creatine, since their physiology differs from humans so much in this respect. A retrospective study found no difference in liver enzyme levels in athletes who took creatine for as long as four years relative to controls. Another study measured the effects of creatine loading on liver enzyme levels in nationally competitive athletes and found no significant change.
