Could men withbenign prostatic hyperplasia (BPH) join SELECT?
Men with BPH, an abnormal growth of benign prostate cells, could join SELECT because BPH is not a cancerous or precancerous condition. In BPH, the prostate grows larger and presses against the urethra and bladder, interfering with the normal flow of urine. More than half of the men in the United States between the ages of 60 and 70, and as many as 90 percent of men between the ages of 70 and 90, have symptoms of BPH. BPH can be treated with four different FDA-approved drugs: finasteride (Proscar®), terazosin (Hytrin®), doxazosin (Cardura®), and tamsulosin (Flomax®). Most men taking one of these drugs were eligible to participate in SELECT. 8.What tests were used to determine eligibility for SELECT? Tests included a digital rectal examination (DRE) and a prostate-specific antigen (PSA) test. During a DRE, a doctor inserts a gloved finger into the rectum and feels the prostate gland through the rectal wall to check for bumps or abnormal areas. The PSA test measures the level of PSA (a pr
