Could 150 mg of Trazodone and 10 mg of Flexeril cause Serotonin Syndrome?
Cyclobenzaprine is structurally related to the first-generation tricyclic antidepressants such as imipramine and amitriptyline. It therefore should not be used within 14 days of cessation of therapy with monoamine oxidase inhibitors (MAOIs) or with other serotonergic antidepressant drugs (e.g. SSRIs), due to the risk of hyperserotonemia (‘serotonin syndrome’).[3] Trazodone is a psychoactive compound with sedative, anxiolytic, and antidepressant properties. A psychoactive drug or psychotropic substance is a chemical substance that acts primarily upon the central nervous system where it alters brain function, resulting in temporary changes in perception, mood, consciousness and behaviour. The above is a cut and paste from wikipedia; feel free to read more regarding this drug at wikipedia.org The symptoms of being at unease is most likely (in my opinion, is definitely) related to the flexeril. Although the dosage is low, a person who has not taken a psychoactive may experience a heightene
