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In 2008, several Alka-Seltzer Plus® Cold effervescent cold products were reformulated with aspirin. Alka-Seltzer Plus® Original Cold, Cold & Cough, Orange Zest, Cherry, Sinus and Day formula within Day/Night Cold pack contain 325mg of aspirin. Alka-Seltzer Plus® Flu, Night and Night formula within Day/Night Cold pack contain 500mg of aspirin.
