Clinical correlation between effective anticoagulants and risk of stroke: are we using evidence-based strategies?
that can cause stroke by lodging in arteries of the brain. (1) The annual rate of stroke among patients with nonvalvular AF is about 5% per year. (2) If untreated, one in three people with nonvalvular AF will suffer a stroke. (3) The importance and efficacy of anticoagulation therapy in preventing a stroke is common knowledge, and has become the standard of care. (4) The cost-effectiveness of anticoagulation therapy in patients with nonvalvular AF, even in older patients who are more at risk for adverse events, is also well established. Lightowles (5) reported that anticoagulation therapy is most cost-effective in this patient group.
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