Can you tell me the differences in benefits of high-dose interferons (Betaseron® and Rebif®) and AVONEX?
Controversy exists among experts concerning whether or not there is any benefit to using a “higher dose of interferon” than the dose provided by AVONEX. Most available studies show little or no difference between the different interferon products based on the way we currently measure drug effectiveness. Until studies show a clear-cut difference in effectiveness between these products, which in my opinion seems to be unlikely to occur, the controversy of whether a higher dose of interferon is more effective will most likely continue. In fact, in a study conducted with AVONEX giving 30 mcg vs. 60 mcg doses, there was an increase in side effects with a higher dose. Effectiveness was similar between the regular dose of AVONEX and the higher dose of AVONEX.
Related Questions
- What are some differences between AVONEX, Betaseron® (Interferon beta-1b), Rebif® (Interferon beta-1a), and Copaxone® (Glatiramer acetate injection)?
- Can you tell me the differences in benefits of high-dose interferons (Betaseron® and Rebif®) and AVONEX?
- What are the primary differences between the two benefits?
