Can you give me more facts on animal testing?
The practice of animal testing is regulated to various extents in different countries. In 1984 the WHO’s Council for International Organizations of Medical Sciences (CIOMS) issued International Guiding Principles for Biomedical Research Involving Animals, and developed countries have developed regulatory frameworks that are more extensive. In the United States and in many other countries, review committees serve as gatekeepers for determining whether the use of animals proposed is warranted. They examine protocols to see if these can be improved by reducing or replacing animal use, and aim to minimize suffering. The trend in developed nations to offshore trials in biomedical research has also affected preclinical testing on animals, although to a lesser extent than clinical trials on humans.