Can you expalin to me what macrocytosis is all about?
Macrocytosis is the enlargement of red blood cells with near-constant haemoglobin concentration, and is defined by a mean corpuscular volume (MCV) of greater than 100 femtolitres (the precise criterion varies between laboratories). this means larger than normal red blood cells [edit] Causes Most commonly (especially when the increase in size is mild, and just above normal range) the etiology is bone marrow dysplasia primary to alcohol abuse. Other causes may include: Megaloblastosis (Vitamin B12 or folate deficiency; or DNA synthesis-inbiting drugs) hypothyroidism reticulocytosis (commonly from hemolysis or a recent history of blood loss). liver disease myeloproliferative disease [edit] Complications No complications arise from macrocytosis itself and a prognosis will be determined from its aetiology Generally speaking, macrocytosis affects the kidneys because the enlarged cells sort of “clog” up the tubes so to speak inside the kidneys. Depending on the severity of the macrocytosis, i
