Can women obtain enough tocotrienols to reduce breast cancer risk?
For those seeking to use tocotrienols to reduce breast cancer risk, it is essential to quantify the optimal daily dose. In humans not consuming tocotrienol supplements, the average plasma concentration is less than 1 microgram per liter of blood.[45-47] After supplementation with a palm-oil concentrate containing about 78 milligrams of tocotrienols for four weeks, plasma tocotrienol levels increased to 8.14 micrograms per liter of blood (an eight-fold increase).[47] It is especially important to take the tocotrienols with some form of oil or fat-containing food. One study showed that when tocotrienols are taken on an empty stomach, absorption was reduced by an average of 64%.44 When taking gamma tocopherol and/or tocotrienol vitamin E supplements, try to take them with a meal or with fatty acid capsules like fish oil (EPA-DHA), GLA, CLA etc. This plasma concentration of 8.14ug/l of tocotrienol is similar to the amount used to achieve an inhibitory effect on the proliferation of estroge
