Can WHO therapy failure criteria for non-severe pneumonia be improved in children aged 2-59 months?
Author(s): Hazir T, Qazi SA, Nisar YB, Maqbool S, Asghar R, Iqbal I, Khalid S, Randhawa S, Aslam S, Riaz S, Abbasi S Affiliation(s): Children’s Hospital, Pakistan Institute of Medical Sciences, Islamabad, Pakistan. arichi99@ariresearch.edu.pk Publication date & source: 2006-08, Int J Tuberc Lung Dis., 10(8):924-31. Publication type: Multicenter Study; Randomized Controlled Trial SETTING: In the recent past, there have been reports of rising treatment failure rates for non-severe pneumonia. It is felt that World Health Organization (WHO) criteria for therapy failure are too sensitive and that many children are unnecessarily classified as failures. We studied alternative, less sensitive therapy failure criteria. METHODS: In this nested study we followed the clinical course of non-severe pneumonia in children aged 2-59 months using alternative therapy failure criteria. All children received amoxicillin and were followed up on days 3, 5 and 14 after enrollment. On day 3, children were labe
