Can we reconcile metabolic acidosis and nutritional status in hemodialysis patients?
Am Soc Nephrol J Am Soc Nephrol (abstract) (Nov) 6:571 1995 Although acidosis has been shown to adversely affect muscle protein metabolism, there is little clinical information available about the inter-relations of acidosis and nutritional indices in dialysis patients. Acchiardo et al. measured predialysis serum HCO3, PCRn, Kt/V, dietary protein intake, serum albumin and serum phosphorus in 131 dialysis patients. Patients with low serum HCO3 levels (mean 18.4) had higher PCRn and DPI, as well as higher serum phosphorus levels than those with higher HCO3 levels. Serum albumin averaged 4.0, and weight and hematocrit were stable in patients with “low” HCO3. Comment: Mild degrees of metabolic acidosis are not associated with adverse nutritional status. (Daugirdas) To go back use the BACK button on your browser.