Can we perform the SpermMar IgG test on washed spermcells ?
We advice against washing the spermcells before performing the direct SpermMar IgG test for a number of reasons. First of all, some washing media contain human serum albumin (HSA). HSA tends to form a “shield” around the spermcells which hide the antibodies so that they can not be detected by the test method. Secondly, washing the sperm sample will remove most of the antibodies that could be present in the seminal plasma and might thus render false negative results.