Can we give Rh positive components to Rh negative patients?
RED BLOOD CELLS: Yes, if it is an emergency or if large amounts of blood may be used. PLATELETS: ABO and Rh compatible platelets will be released for transfusion. If this is not feasible because of limited inventory and /or emergent need for the component, ABO and /or Rh incompatible platelets may be issued. It may be advisable to administer Rho (D) immune globulin to selected Rh-negative patients who receive platelets from Rh-positive donors, since sensitization to red cell antigens may occur from the few red cells present in platelets.