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Can the mouse CD1d tetramer be used with human samples?

April 26, 2017cd1d Human mouse samples tetramer Used

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Can the mouse CD1d tetramer be used with human samples?

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While the mouse CD1d tetramer is cross-reactive with human cells, it is not recommended for use with human samples. The unloaded mouse CD1d tetramer can show a high background stain when used on human samples making any comparative data with the loaded tetramer difficult to interpret.