Can the metabolite molecules that are considered markers of nitrofurans, originate from other sources than nitrofuran use?
AOZ is specifically indicated as the marker residue for furazolidone (see FAQ6), other markers for other nitrofurans are indicated in literature and have been derived from the parent drug molecular structure in analogy with furazolidone. Before using SEM, which is a very small molecule, as a marker for nitrofurazone, an extensive literature survey was conducted, this survey did not reveal any other known naturally occurring source or precursor of SEM.
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