Can the instructors change any of the grades?
No. Entering grades is based on the various authorizations done the course director or administrator. Typically, the “course director” has access to everything, including the ability to download and upload the spreadsheets. A “teacher” can be also authorized to access practically anything (except download/upload). An instructor responsible to a particular grading unit can change the grades belonging to that unit only. For example, a lab instructor can not enter or change homework grades.