Can the GenePORTER reagents be used for in-vivo experiments?
The GenePORTER and the GenePORTER 2 cells transfection reagents have been successfully demonstrated to enhance gene expression in various mouse models including direct muscular injections and intratumoral injections. Follow the standard protocol for formulation of the DNA/GenePORTER complexes. Also, see Bogdanov, et. al. (2001) Gene Therapy 8, 515-522.