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Can the GenePORTER reagents be used for delivering oligonucleotides?

April 26, 2017geneporter oligonucleotides reagents Used

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Can the GenePORTER reagents be used for delivering oligonucleotides?

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The GenePORTER reagent is recommended for delivery of oligonucleotides (though the GenePORTER 2 reagent has also been used for this application). The GenePORTER reagents have been shown to deliver phosphothioate oligonucleotides into cells with ease. Also, the GenePORTER reagents have been used to deliver 20-mer to 80-mer oligos into a variety of mammalian cell lines. (Note: It is not recommended to use the GenePORTER reagents with neutral or positively charged DNA analogues.

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Posted

The GenePORTER reagent is recommended for delivery of oligonucleotides (though the GenePORTER 2 reagent has also been used for this application). The GenePORTER reagents have been shown to deliver phosphothioate oligonucleotides into cells with ease. Also, the GenePORTER reagents have been used to deliver 20-mer to 80-mer oligos into a variety of mammalian cell lines.