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Can the bands be removed and analyzed by mass spectrometry following staining?

April 26, 2017analyzed bands mass removed spectrometry staining

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Can the bands be removed and analyzed by mass spectrometry following staining?

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Yes. See Tech Tip #50: Process stained polyacrylamide gels for mass spectrometry. Alternatively, use our Pierce Silver Stain for MS (#24600), which is the same silver stain kit but also includes destaining reagents and a protocol optimized for maximum protein recovery.