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Can thalassemia major patients marry and have children?

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Can thalassemia major patients marry and have children?

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Fertility has been reported worldwide in well-treated thalassemia patients. If a thalassemia major patient marries a carrier, then there will be 50% risk of thalassemia major in offspring and will require prenatal diagnosis. If a thalassemia major female marries a normal male, who is neither carrier nor affected, then they can have asymptomatic (normal/carrier) children. Assisted reproductive techniques may be required in some of the cases.

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