Can Telomere Length Predict Life Span?
Yes. A long telomere at the end of a chromosome allows for cells to continue dividing. Every time the cell divides and replicates its DNA, telomeres get shorter, and once they reach a critical length, a length not yet completely known, the cell has a difficult time continuing to replicate the DNA properly. When DNA is unable to properly replicate, a cell either undergoes cell death, or potentially worse, continues to stay alive and functions poorly. Poorly functioning cells can alter a healthy physiological balance in the body. A number of studies have now shown that short telomeres are related to the development of diabetes, cardiovascular disease, vulnerability to infections and even earlier mortality. “Telomere length is increasingly considered a biological marker of the accumulated wear and tear of living, integrating genetic influences, lifestyle behaviors and stress,” says Dr. Epel.