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Can tandem provide dual modifications like an ICAT experiment?

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Can tandem provide dual modifications like an ICAT experiment?

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Tandem will allow two modifications on the same residue like in an ICAT experiment. The following is taken from the API description of the residue, modification mass parameter: If a residue labelling strategy is being used where there are two types of reagents for modifying a residue (e.g., C), one with mass L1 and the other with mass L2, the following method can be used to find both types of labelled peptide in the same analysis.

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