Can Singulair be used for capsular contracture associated with breast implants?
• A: Singulair (montelukast) is a leukotriene inhibitor that is used for the treatment of asthma and allergies. Leukotrienes are chemicals in the body that are released as part of the allergic response. Capsular contracture is an abnormal response of the immune system to foreign materials, including breast implants. The treatment of capsular contracture with leukotriene inhibitors (including Singulair and Accolate [zafirlukast]) has been reported in the medical literature. Anecdotal reports have shown that zafirlukast and montelukast may reverse capsular contracture. These reports have not been confirmed in scientific studies and this use of leukotriene inhibitors is not approved by the US Food and Drug Administration. For more information, please contact your healthcare provider.
