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Can sensitivity be improved by extending the exposure time?

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Can sensitivity be improved by extending the exposure time?

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The signal from a sample is integrated over time. The sensitivity improves with exposure time, but only up to a point. The instrument noise dramatically affects the linearity of the CCD at low-light intensity and long exposure. The VDS-CL has a cooled CCD that significantly reduces the noise. However, exposures longer than 30 min do not improve the sensitivity.

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