Can SAM-e and glucosamine be used with prescription products?
Since neither SAM-e nor glucosamine have shown negative interactions, SAM-e and glucosamine are safe to use with other products. In fact, both products are often recommended when prescription side effects are unacceptable. Additionally, because of its protective qualities, SAM-e plus glucosamine may be a beneficial addition to joint remedies like NSAIDs, which may cause long-term damage.